RECENT PUBLICATIONS

  • Steinhorn B, Eroglu E, Michel T. Chemogenetic Approaches to Probe Redox Pathways: Implications for Cardiovascular Pharmacology and Toxicology. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:551-571. doi: 10.1146/annurev-pharmtox-012221-082339. Epub 2021 Sep 16. PMID: 34530645. PubMed link
  • Spyropoulos F, Sorrentino A, van der Reest J, Yang P, Waldeck-Weiermair M, Steinhorn B, Eroglu E, Saeedi Saravi SS, Yu P, Haigis M, Christou H, Michel T. Metabolomic and transcriptomic signatures of chemogenetic heart failure. Am J Physiol Heart Circ Physiol. 2022 Mar 1;322(3):H451-H465. doi: 10.1152/ajpheart.00628.2021. Epub 2022 Jan 28. PMID: 35089810. PubMed link
  • Waldeck-Weiermair M, Yadav S, Spyropoulos F, Krüger C, Pandey AK, Michel T. Dissecting in vivo and in vitro redox responses using chemogenetics. Free Radic Biol Med. 2021 Dec;177:360-369. doi: 10.1016/j.freeradbiomed.2021.11.006. Epub 2021 Nov 6. PMID: 34752919; PMCID: PMC8639655.   PubMed link
  • Erdogan YC, Altun HY, Secilmis M, Ata BN, Sevimli G, Cokluk Z, Zaki AG, Sezen S, Akgul Caglar T, Sevgen İ, Steinhorn B, Ai H, Öztürk G, Belousov VV, Michel T, Eroglu E. Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting. Free Radic Biol Med. 2021 Dec;177:132-142. doi: 10.1016/j.freeradbiomed.2021.10.023. Epub 2021 Oct 20. PMID: 34687864; PMCID: PMC8639799.  PubMed link
  • Saeedi Saravi SS, Eroglu E, Waldeck-Weiermair M, Sorrentino A, Steinhorn B, Belousov V, Michel T. Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis. Redox Biol. 2020 Sep;36:101605. doi: 10.1016/j.redox.2020.101605. Epub 2020 Jun 16. PMID: 32590330; PMCID: PMC7322171.  PubMed link
  • Pak VV…Michel T, Vriz S, Messens J, Belousov VV. Ultrasensitive genetically encoded indicator for intracellular hydrogen peroxide identifies novel roles for cellular oxidants in cell migration and mitochondrial function. Cell Metabolism 2020, 31:642-653. PubMed link
  • Sorrentino A and Michel T. Redox a la Carte: Novel chemogenetic models of heart failure.  British Journal of Pharmacology 2020, DOI: 10.1111/bph.15093. PubMed link
  • Saravi S, Eroglu E, Waldeck-Weiermair M, Sorrentino A, Steinhorn B, Belousov V, Michel T. Differential endothelial signaling responses elicited by chemogenetic hydrogen peroxide synthesis.  Redox Biology 2020, 36:101605, https://doi.org/10.1016/j.redox.2020.101605. PubMed link
  • Sorrentino A, Steinhorn B, Troncone L, Badole SL, Saravi SSS, Eroglu E, Kijewski MF, Divakaran S, Di Carli M, Michel T. Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress. Am J Physiol Heart Circ Physiol. 2019 317: H617-H626. PMCID:PMC6766720.  PubMed link
  • Eroglu E, Saravi S, Sorrentino A, Steinhorn B, Michel T. Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods.  Proc Natl Acad Sci USA 2019, 116:20210-20217. PMID: 31527268. PubMed link