Who am I?
I am a Senior Physician in cardiovascular medicine at Brigham and Women’s Hospital (BWH). I am also a Professor of Medicine (Biochemistry) at Harvard Medical School (HMS), Co-Director of the Leder Human Biology and Translational Medicine Program at HMS, and serve on the leadership council of the Harvard/Massachusetts Institute of Technology MD-PhD Program.
After graduating from Harvard College, I received my MD and PhD degrees from Duke University School of Medicine. I completed an internal medicine residency, a clinical cardiology fellowship and a genetics research fellowship at BWH. I am board certified in internal medicine and cardiovascular disease.
My clinical interests include general cardiology and ischemic heart disease. I have authored of over 160 peer-reviewed publications, our research uses biochemical and cell biological approaches to understand signal transduction pathways in the cardiovascular system. My laboratory has studied endothelial nitric oxide synthase (eNOS), a signaling enzyme involved in the control of vascular tone, myocardial contractibility and platelet aggregation. My lab has also studied the roles of reactive oxygen species in physiological and pathophysiological pathways in the heart and vasculature. The National Institutes of Health has provided continuous funding for my research endeavors for the past two decades. I am also active as an educator at HMS.