Here you can find some of our recent publications. To see more of our work go to original articles or selected reviews.
- Spyropoulos F, Michel T. D-Amino acid oxidase-derived chemogenetic oxidative stress: Unraveling the multi-omic responses to in vivo redox stress. Curr Opin Chem Biol. 2024;79:102438. doi:10.1016/j.cbpa.2024.102438
- Yadav S, Waldeck-Weiermair M, Spyropoulos F, et al. Sensory ataxia and cardiac hypertrophy caused by neurovascular oxidative stress in chemogenetic transgenic mouse lines. Nat Commun. 2023;14(1):3094. Published 2023 May 29. doi:10.1038/s41467-023-38961-0
- Steinhorn B, Eroglu E, Michel T. Chemogenetic Approaches to Probe Redox Pathways: Implications for Cardiovascular Pharmacology and Toxicology. Annu Rev Pharmacol Toxicol. 2022;62:551-571. doi:10.1146/annurev-pharmtox-012221-082339
- Spyropoulos F, Sorrentino A, van der Reest J, et al. Metabolomic and transcriptomic signatures of chemogenetic heart failure. Am J Physiol Heart Circ Physiol. 2022;322(3):H451-H465. doi:10.1152/ajpheart.00628.2021
- Waldeck-Weiermair M, Yadav S, Spyropoulos F, Krüger C, Pandey AK, Michel T. Dissecting in vivo and in vitro redox responses using chemogenetics. Free Radic Biol Med. 2021;177:360-369. doi:10.1016/j.freeradbiomed.2021.11.006
- Erdogan YC, Altun HY, Secilmis M, et al. Complexities of the chemogenetic toolkit: Differential mDAAO activation by d-amino substrates and subcellular targeting. Free Radic Biol Med. 2021;177:132-142. doi:10.1016/j.freeradbiomed.2021.10.023
- Saeedi Saravi SS, Eroglu E, Waldeck-Weiermair M, et al. Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis. Redox Biol. 2020;36:101605. doi:10.1016/j.redox.2020.101605
- Sorrentino A, Michel T. Redox à la carte: Novel chemogenetic models of heart failure. Br J Pharmacol. 2020;177(14):3162-3167. doi:10.1111/bph.15093
- Saeedi Saravi SS, Eroglu E, Waldeck-Weiermair M, et al. Differential endothelial signaling responses elicited by chemogenetic H2O2 synthesis. Redox Biol. 2020;36:101605. doi:10.1016/j.redox.2020.101605
- Sorrentino A, Steinhorn B, Troncone L, et al. Reversal of heart failure in a chemogenetic model of persistent cardiac redox stress. Am J Physiol Heart Circ Physiol. 2019;317(3):H617-H626. doi:10.1152/ajpheart.00177.2019
- Eroglu E, Saravi SSS, Sorrentino A, Steinhorn B, Michel T. Discordance between eNOS phosphorylation and activation revealed by multispectral imaging and chemogenetic methods. Proc Natl Acad Sci U S A. 2019;116(40):20210-20217. doi:10.1073/pnas.1910942116